WebA mathematical analysis of the factors affecting thiopental redistribution in the human body after a single intravenous injection of the drug has been devised and presented. Concentration ratios of thiopental predicted mathematically were compared with those obtained by the direct measurement of concentrations in human blood and fat. WebMar 17, 2024 · Thiopental powder for solution for injection - Summary of Product Characteristics (SmPC) - (emc) Thiopental powder for solution for injection Active Ingredient: thiopental sodium Company: ADVANZ Pharma See contact details ATC code: N01AF03 About Medicine Prescription only medicine Healthcare Professionals (SmPC) …
Drug Distribution to Tissues - Merck Manuals Professional Edition
WebRapidly partition into the brain Act briefly and then redistributes into other tissues -- often ultimately concentrating in adipose tissue. Redistribution is the mechanism responsible for termination of action of thiopental (pentothal) or propofol (Diprivan), anesthetic inducing agents. http://www.metrohealthanesthesia.com/edu/ivanes/barbiturates1.htm open an account with hsbc online
The pharmacokinetics of thiopentone - PubMed
WebFor example, thiopental is highly lipid soluble, rapidly enters the brain after a single IV injection, and has a marked and rapid anesthetic effect; the effect ends within a few minutes as the drug is redistributed to more slowly perfused fatty tissues. Thiopental is then slowly released from fat storage, maintaining subanesthetic plasma levels. WebJun 1, 2004 · The metabolism of thiopental is normally a first-order process; however, once plasma concentrations exceed a certain value, the enzyme system becomes saturated and metabolism becomes a zero-order … Webthiopental (ULTRA-SHORT acting) What is thiopental used for what? induce anesthesia in dogs, cats, and horses Phenobarbital is used for what? treat seizures What are barbiturates used primarily for? induction agents due to rapid onset and effect T/F: You an use barbiturates for short surgical procedures. TRUE open an account with ptsb