Mouse parotid gland

Author: beks

August undefined, 2024

NettetSummaryAutomatic TranslationFebruary 8th, 2011. An optimized protocol for the isolation of stem cells from the mouse salivary gland is described. The method employs enzymatic and mechanical digestion, and permits isolation of salispheres containing cells with characteristics of stem cells. NettetThe submandibular glands (SMGs) contribute to 65% of the unstimulated saliva, 20% is produced by the parotid gland (PG) and 7%–8% by the sublingual glands (SLG) …

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NettetOur recent studies have used mouse parotid gland (PG) cells, grown on different extracellular matrices, as a model for acinar formation. However, PG cells were not able to respond to the secretory agonist carbachol beyond 5 days and did not sustain polarity over time, regardless of the substratum. NettetOur recent studies have used mouse parotid gland (PG) cells, grown on different extracellular matrices, as a model for acinar formation. However, PG cells were not … borne oxhoo

Cancer stem cell markers in adenocarcinoma of the salivary glands ...

NettetWe also observed that mouse parotid glands contain high levels of peroxisomal β-oxidation enzymes (including Acox1, Mfp2 and Acaa1), catalase and other peroxisomal … NettetSjogren's syndrome (SS) is a chronic heterogeneous disease that mainly affects exocrine glands, leading to sicca syndromes such as xerostomia. Despite the seco Nettet1. apr. 2016 · Abstract. Macroscopic identification and surgical removal of the mouse parotid gland is demanding because of its anatomic location and size. Moreover, the … borne p17

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Nettet3. jan. 2024 · Catalán, M. A. et al. A fluid secretion pathway unmasked by acinar-specific Tmem16A gene ablation in the adult mouse salivary gland. Proc. Natl. Acad. Sci. USA 112, 2263–2268 (2015). NettetMurine parotid gland organoids harbor stem cells with long-term expansion and differentiation potential. This model is useful for mechanistic studies of stem cell … haven holidays gowerNettetThe parotid gland (glandula parotidea) is one of the major salivary glands present in humans and rodents. The secretory cells of the parotid acini mainly produce serous … borneperfect

"NettetSaliva is mostly produced by the major salivary glands, namely the parotid, submandibular, and sublingual glands. The submandibu-lar glands (SMGs) contribute … " - Mouse parotid gland

Mouse parotid gland

Acinar Cell Proliferation Promoted by BMP2 in Injured Mouse Parotid ...

Nettet16. nov. 2016 · Mouse models have served a valuable role in deciphering various facets of Salivary Gland (SG) biology, from normal developmental programs to diseased states. To facilitate such studies, gene expression profiling maps have been generated for various stages of SG organogenesis. NettetA preliminary evaluation of the parotid secretion cellular composition in patients with Sjogren’s Syndrome (SS) and a diagnostic accuracy assessment of salivary lymphocyte detection and immunophenotyping in Sjogren’s Syndrome diagnosis and prognosis were performed. The study included 40 consecutive patients, aged 19–60 years, with …

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Nettet1. nov. 2024 · The parotid gland produces a serous salivary secretion that has several functions in the digestive and immune system ( Omon and Shiga, 1986 ). Another … NettetSaliva secretion requires effective translocation of aquaporin 5 (AQP5) water channel to the salivary glands (SGs) acinar apical membrane. Patients with Sjögren’s syndrome (SS) display abnormal AQP5 localization within acinar cells from SGs that correlate with sicca manifestation and glands hypofunction. Several proteins such as Prolactin …

Nettet31. mar. 2024 · Objective: To identify factors that affect salivary gland recovery, we investigated the expression and function of bone morphogenetic protein 2 (BMP2) in … NettetThere are three pairs of major salivary glands in mice and humans, submandibular (SMG), sublingual (SLG) and parotid (PG) glands. In mice, the acini of SMG are seromucous, with additional secretory (serous) cells in a segment of the ducts called the granular convoluted tubules, SLG tubulo-acini are mucous with serous caps or …

Nettet12. apr. 2024 · HIGHLIGHTS. who: Parotid Gland and collaborators from the Department of Physiology, Nihon University School of Dentistry at Matsudo, Chiba, Japan have published the article: Acinar Cell Proliferation Promoted by BMP2 in Injured Mouse Parotid Gland: BMP2 Promotes Cell Proliferation in Parotid Gland, in the Journal: … Nettet20. mar. 2024 · Also, a near-physiological salivary gland with correct structure and secretory function was regenerated in vivo from hSMGepiS/PCs plus mouse E12.5 salivary gland mesenchyme. Therefore, the dynamic niche in the developing mouse embryonic salivary gland facilitates the organogenesis of salivary glands from …

Nettet11. jan. 2016 · To enable further investigation of salivary gland cell lineages and their origins, we generated three cell-specific Cre driver mouse strains. For genetic manipulation in acinar cells, an inducible Cre recombinase (Cre-ER) was targeted to the prolactin-induced protein ( Pip) gene locus.

Nettet26. okt. 2010 · In intact rats, Ad.hPTH was infused into the salivary glands: 5 × 10 9 or 5 × 10 10 VP per gland (parotid) or 5 × 10 9 VP per gland (submandibular). Two days later, when adenovirus-mediated transgene expression in rat parotid glands is near maximal (Kagami et al. , 1998 ), blood and saliva were collected and assayed for hPTH ( Fig. 2A … borne panlaireNettet20. feb. 2024 · This well-characterized mouse salivary gland cell line will fill a critical void in the field by offering a valuable resource to examine various mechanistic aspects of mouse salivary gland biology. Citation: Min S, Song E-AC, Oyelakin A, Gluck C, Smalley K, Romano R-A (2024) Functional characterization and genomic studies of a novel … haven holidays burnham on sea somersetNettetThe parotid salivary glands are classified as serous glands, the sublingual salivary glands as mucous glands and the submaxillary (submandibular) as mixed glands. … haven holidays exmouth sandy bay