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WebApr 11, 2024 · Homocysteine is an endogenous, non-protein sulfuric amino acid, an intermediate metabolite formed by the methionine transmethylation reaction. Its elevated serum concentration in humans, hyperhomocysteinemia, is a sensitive indicator and a risk factor for coagulation disorders, cardiovascular diseases and dementia. However, the role … WebAug 11, 2016 · With the development of intravital imaging techniques, animal models that closely mimic the pathogenesis of thrombosis in humans, and selective antagonists of leukocyte-regulated procoagulant pathways, the role that leukocytes play in regulating thrombosis is being unveiled. WebNormally, a blood clots start as a response to injury of a blood vessel. At first, the blood stays in one place. Two substances — platelets (a type of blood cell) and fibrin (a firm string-like substance) — combine to form what is called a platelet plug to stop up the cut or hole. how many gb is elder scrolls online