WebFoxM1B in hepatocytes or contained a hepatocyte-spe-cific deletion of the Foxm1b allele demonstrated that FoxM1B is critical for regulating the expression of cell cycle genes required for hepatocyte proliferation. Fur-thermore, preventing the decline in hepatocyte FoxM1B levels during aging was sufficient to increase regener- WebApr 7, 2024 · FoxM1b is a cell cycle-regulated transcription factor, whose over-expression is a marker for poor outcome in cancers. Its transcriptional activation function requires …
FoxM1B Regulates NEDD4-1 Expression, Leading to Cellular …
WebJan 31, 2013 · FOXM1c is distinguished from FOXM1b by an extra exon (exon Va) that contains an ERK1/2 target sequence. Based on a literature search and quantitative PCR … WebSep 18, 2003 · FoxM1B Tg mice were subjected to the experimental protocol described in the legend of Figure 1. Sections are representative of the observation that a high rate of … hugo alignment
Plk1 Regulates the Repressor Function of FoxM1b by …
WebMar 21, 2024 · FOXB1 (Forkhead Box B1) is a Protein Coding gene. Diseases associated with FOXB1 include Wernicke-Korsakoff Syndrome and Thiamine Deficiency Disease . … WebThe delayed early transcription factor Forkhead Box M1B (FoxM1B) is expressed in proliferating cells, but its expression is extinguished in cells undergoing terminal differentiation. Liver regeneration studies with genetically altered mice that either prematurely expressed FoxM1B in hepatocytes or contained a hepatocyte-specific … WebSep 25, 2001 · Furthermore, FoxM1B provided a 2.8-fold induction in cyclin D1 promoter expression in HepG2 cell cotransfection assays (Fig. 5). These studies demonstrated that FoxM1B is able to transcriptionally activate the cyclin B1 and cyclin D1 promoters, suggesting that FoxM1B functions to directly regulate transcription of these cyclin genes. hugo alfven