WebJan 24, 2024 · Here, we reviewed the recent advances of applying the rational design strategy to engineer enzyme functions including activity and enantioselectivity. Five strategies including multiple sequence alignment, strategy based on steric hindrance, strategy based on remodeling interaction network, strategy based on dynamics … WebNational Center for Biotechnology Information
Enantioselective (8+3) Cycloadditions by ... - Wiley Online Library
WebMar 18, 2024 · A “holistic prediction of enantioselectivity in asymmetric catalysis” was presented by Reid et al., in Nature in 2024. 44 The enantioselectivity data proceedings from a combination of BINOL-derived chiral phosphoric acids and different nucleophilic addition reactions to imines were used to validate the statistical models produced. These ... WebApr 1, 2024 · No obvious enantioselectivity in the degradation of mefentrifluconazole was observed in control group (without earthworm) and treatment group (with earthworm), with EF values of approximately 0.5. A similar study reported that there is no preferential degradation of single enantiomer of mefentrifluconazole in soil ( European Food Safety … persia and assyria
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WebMar 30, 2024 · Enantioselectivity prediction in asymmetric catalysis is a long-standing challenge in synthetic chemistry. Now, a data-driven workflow is designed to implement transition state knowledge in ... WebStyrene monooxygenases (SMOs) are powerful enzymes for the synthesis of enantiopure epoxides, but these SMOs have narrow substrate spectra, and the residues in controlling enantioselectivity of SMOs remains unclear. A monooxygenase from Herbaspirillum huttiense (HhMO) was found to have excellent ena … WebDue to the strict enantioselectivity of firefly luciferase, only d-luciferin can be used as a substrate for bioluminescence reactions. l-luciferin is known as a strong competitive … persia ancient artifacts