Chlamydomonas hap2
WebThe structure of Chlamydomonas HAP2 suggests that the cd loop is bipartite, with the two parts split by a small alpha helix (Fe´dry et al., 2024). Given this specific structure/function biological activity observed during the study of HAP2 in Tetrahymena, Arabidopsis, and Chlamydomonas, and the general conservation of the protein WebFeb 28, 2024 · X-ray crystallography reveals that two closely related proteins, the HAP2 protein from the single-celled alga Chlamydomonas reinhardtii and the fusion protein from dengue virus are essential for fusion with a cell membrane and thus both sexual reproduction and viral invasion of a host cell. The proteins probably emerged very early …
Chlamydomonas hap2
Did you know?
WebMay 3, 2024 · HAP2 is a class II gamete fusogen in many eukaryotic kingdoms. A crystal structure of Chlamydomonas HAP2 shows a trimeric fusion state. Domains D1, D2.1 … WebNational Center for Biotechnology Information
WebHAP2 is a class II gamete fusogen in many eukaryotic kingdoms. A crystal structure of Chlamydomonas HAP2 shows a trimeric fusion state. Domains D1, D2.1 and D2.2 line the 3-fold axis; D3 and a ... WebOct 3, 2024 · HAP2 is a class II gamete fusogen in many eukaryotic kingdoms. A crystal structure of Chlamydomonas HAP2 shows a trimeric fusion state. Domains D1, D2.1 …
WebMay 3, 2024 · 6DBS. PubMed Abstract: HAP2 is a class II gamete fusogen in many eukaryotic kingdoms. A crystal structure of Chlamydomonas HAP2 shows a trimeric fusion state. Domains D1, D2.1 and D2.2 line the 3-fold axis; D3 and a stem pack against the outer surface. Surprisingly, hydrogen-deuterium exchange shows that surfaces of D1, D2 ... WebHAP2 gene knockouts in Chlamydomonas resulted in gametes of opposing mating types-mt (+) and mt (−)-to adhere to each other, but membrane fusion and thus fertilization was abrogated [22]. In...
WebNov 22, 2024 · Gamete fusion in organisms across kingdoms depends on fusogen HAP2. Pinello et al. demonstrate that receptor MAR1 is associated with HAP2 on Chlamydomonas minus gametes and binds to conserved adhesion protein FUS1/GEX2 on plus gametes, suggesting a mechanism that ensures that bilayer merger is triggered only …
WebJan 10, 2024 · HAP2/GCS1 proteins share a similar structure with two distinct families of exoplasmic fusogens: the somatic Fusion Family (FF) proteins discovered in nematodes, … csulb champion hoodieWebHAP2 localizes at the fusion site of Chlamydomonas minus gametes, yet Chlamydomonas minus and Plasmodium hap2 male gametes retain the ability, using … early tecumseh engine model number locationWebFeb 23, 2024 · "The HAP2 protein from Chlamydomonas is folded in an identical fashion to the viral proteins," Rey said, referring to the molecular folding that creates the three-dimensional structure of all ... earlyteen sabbath school lesson 2021WebChlamydomonas HAP2 is a member of a broadly conserved protein family whose founding member was identified in Arabidopsis in a screen for male sterile mutants (Johnson et al., 2004). [HAP2 more recently has also been termed GCS1 (Mori et al., 2006).] Previously, using gene disruption methods, we showed that in both Chlamydomonas and the rodent earlytect® colon cancerWebOct 3, 2024 · HAP2 is a class II gamete fusogen in many eukaryotic kingdoms. A crystal structure of Chlamydomonas HAP2 shows a trimeric fusion state. Domains D1, D2.1 and D2.2 line the 3-fold axis; D3 and a stem pack against the outer surface. Surprisingly, hydrogen-deuterium exchange shows that surfaces of D1, D2.2 and D3 closest to the 3 … csulb certified specialist in planned givingWebMay 1, 2010 · Chlamydomonas HAP2 is a member of a broadly conserved protein family whose founding member was identified in Arabidopsis in a screen for male sterile … early teenage yearsWebMar 26, 2008 · HAP2. Chlamydomonas, Plasmodium] Fusion of gametes of opposite sex (or mating type) to form a zygote is the defining moment in the life of a eukaryote. In the first … csulb carpenter performing arts center